At Nano Flow, we closely accompany our customers and their products toward high-scale manufacturing. For this perspective, we respect a 4 step-process:
- Definition of the product’s technical specifications and list of Quality Control tests with expected performance criteria.
- Feasibility study including optimization of the passive adsorption conjugation conditions using e.g. antibody quantities as low as 1mg. This integrates identification of best conjugation pH, blocking agent and screening of different antibody concentrations.
- Production scale validation with three QC compliant production batches.
- Gold conjugate production and QC release following expected performance criteria.
Our custom conjugation service also includes support in the selection and sourcing of antibodies, selection of the best nanoparticle size for your specific application, and assistance in the storage buffer optimization and post-delivery technical assistance.